Colloidal Magnetic Silica Nano-/Microspheres
 

• CV< 10 % for Nanospheres below 1 μm and CV< 5% for Microspheres above 1 μm

• Roundness > 0.980, Density: ~2.5 g/cm^3

• Sodium azide can be added as an antimicrobial agent upon request.

• Saturation magnetization: ~20 emu/g

• Provided in Milli-Q water by default or anhydrous ethanol upon request.

• Superparamagnetic cores covered by the silica shells

• Silica shell is optional if the superparamagnetic iron oxide core is needed

• Surface functional group: -OH available for all sizes and -NH2 and -COOH available for 100 nm, 300 nm, and 1 μm

• Low concentrations to ultra-high concentration available: 10 - 100 mg/ml (i.e. 1 - 10 % w/v)

• Sizes available: 100 nm, 300 nm, 500 nm, 1 μm, 2 μm, 5 μm, 10 μm, and 50 μm

• Although applications vary from one to another, 1-10 mg solid magnetic silica microspheres will typically yield 10 μg of DNA molecules 

• Lifetime: At least 2 years from the date of product delivery

• These iron oxide beads coated with silica can be easily surface functionalized via chemical bond formation. The non-functionalized magnetic silica nanoparticles (1 μm being the most popular size) are frequently used for plasmid DNA/RNA isolation/extraction. Carboxyl-functionalized magnetic silica nanoparticles and amine-terminated magnetic silica beads are known to be effective in protein isolation or macromolecule purification.

• Can be adapted to other common biological buffers like phosphate-buffered saline (PBS) or organic solvents like ethanol via repeated centrifugation and resuspension.

• The magnetic silica microspheres might precipitate at the bottom of the containing vial over time, and this is not a sign of aggregation. Large particles precipitate faster than small particles. These particles can be easily resuspended using sonication (ultrasonic bath or ultrasonic homogenizer) or vortexing.

• Our magnetic silica beads are only priced based on the solid content; for instance, 50 ml of the silica nanospheres at 10mg/ml would have the same price as 10 ml of the silica nanospheres at 50 mg/ml.