Colloidal Magnetic Silica Nano-/Microspheres
CV< 10 % for Nanospheres below 1 μm and CV< 5% for Microspheres above 1 μm
Roundness > 0.980, Density: ~2.5 g/cm^3
Sodium azide can be added as an antimicrobial agent upon request.
Saturation magnetization: ~20 emu/g
Provided in Milli-Q water by default or anhydrous ethanol upon request.
Superparamagnetic cores covered by the silica shells
Silica shell is optional if the superparamagnetic iron oxide core is needed
Surface functional group: -OH available for all sizes and -NH2 and -COOH available for 100 nm, 300 nm, and 1 μm
Low concentrations to ultra-high concentration available: 10 - 100 mg/ml (i.e. 1 - 10 % w/v)
Sizes available: 100 nm, 300 nm, 500 nm, 1 μm, 2 μm, 5 μm, 10 μm, and 50 μm
Although applications vary from one to another, 1-10 mg solid magnetic silica microspheres will typically yield 10 μg of DNA molecules
Lifetime: At least 2 years from the date of product delivery
These iron oxide beads coated with silica can be easily surface functionalized via chemical bond formation. The non-functionalized magnetic silica nanoparticles (1 μm being the most popular size) are frequently used for plasmid DNA/RNA isolation/extraction. Carboxyl-functionalized magnetic silica nanoparticles and amine-terminated magnetic silica beads are known to be effective in protein isolation or macromolecule purification.
Can be adapted to other common biological buffers like phosphate-buffered saline (PBS) or organic solvents like ethanol via repeated centrifugation and resuspension.
The magnetic silica microspheres might precipitate at the bottom of the containing vial over time, and this is not a sign of aggregation. Large particles precipitate faster than small particles. These particles can be easily resuspended using sonication (ultrasonic bath or ultrasonic homogenizer) or vortexing.
Our magnetic silica beads are only priced based on the solid content; for instance, 50 ml of the silica nanospheres at 10mg/ml would have the same price as 10 ml of the silica nanospheres at 50 mg/ml.
Fully suspended microspheres when they are away from the magnetic field
Aggregated microspheres at the poles when they are in the magnetic field
Our colloidal magnetic silica beads & microspheres respond to the magnetic field, enabling many laboratory and commercial applications. These microspheres can be repetitively used and easily coupled with other surface moieties for further functionalizations.
Scanning/Transmission Electron Micrographs
Zeta Potential Measurements at pH 7 for Hydroxyl-, Carboxyl-, and Amine-Terminated Magnetic Silica Beads & Microspheres
Hydroxyl-Terminated Magnetic Silica Microspheres
Carboxyl-Terminated Magnetic Silica Microspheres
Amine-Terminated Magnetic Silica Microspheres
Zeta Potential Measurements at Different pH for Hydroxyl-Terminated Magnetic Silica Beads & Microspheres
Fourier-transform infrared spectroscopy (FTIR) measurement results
Our Colloidal Magnetic Silica Nano-/Microspheres in Stock:
100 nm, Hydroxyl-Terminated
100 nm, Carboxyl-Terminated
100 nm, Amine-Terminated
300 nm, Hydroxyl-Terminated
300 nm, Carboxyl-Terminated
300 nm, Amine-Terminated
1 μm, Hydroxyl-Terminated
1 μm, Carboxyl-Terminated
1 μm, Amine-Terminated
2 μm, Hydroxyl-Terminated
5 μm, Hydroxyl-Terminated
10 μm, Hydroxyl-Terminated
50 μm, Hydroxyl-Terminated
10 ml at 10 mg/ml
20 ml at 10 mg/ml
10 ml at 50 mg/ml
Daily Exchange Rates
(updated every 12 hr)
1. SDS (Material Safety Data Sheet) and COA (Certificate of Analysis) are included in every purchase.
2. The prices listed above are in Canadian Dollars (CND$), and please refer to the above exchange box for the most current daily exchange rates.
3. We accept both online purchases at our online store or Amazon stores and invoiced orders (Net 30 Terms). In-stock items will be dispatched within 1-2 business days. The lead time for customized orders is typically within 10 business days and will be evaluated on a case-by-case basis.
4. Shipping Locations for our clients are listed below.
Orders destined for the United States will be shipped from one of the two US offices below.
Unit 390, 701 Harrison Ave, Blaine, WA 98230 US
Unit 4, 2045 Niagara Falls Blvd, Niagara Falls, NY 14304 US
Orders destined for the UK will be shipped from our UK office.
Office 24743, Courier Point, 13 Freeland Park, Wareham Road, Poole, Dorset, BH16 6FH, UK
Orders destined for Europe will be shipped from our EU office.
Allée Primavera 78, Annecy, Pringy, 74370, France
Orders destined for Canada and other International destinations will be shipped from our Canadian headquarters.
135 - 3800 Wesbrook Mall, University of British Columbia Campus, Vancouver, BC, V6S2L9, Canada
No duties or any additional taxes for the orders delivered to Canadian, US, UK, and EU addresses, regardless of the sales channel. For other International shipping addresses, recipients are responsible for local duties and taxes.
5. Free exchanges or full refunds will be offered within 30 days after the order fulfillment without any questions asked if the ordered items fail to meet customer expectations.